Sindeev S.V., Frolov S.V., Liepsch D.Experimental Setups for Studies of Blood Flow in Arteries of Cardiovascular System // Journal "Problems of Contemporary Science and Practice" Vernadsky University , Tambov. TSTU publisher house , 2017. (pdf-file) Abstract: Hemodynamics plays an important role in genesis of
such vascular diseases as atherosclerosis, thrombosis and aneurysm.
The better understanding of flow conditions in the regions which
prone to have such diseases helps a physician in clinical decisionmaking
process. In this study, we present a detailed description of
two experimental setups for evaluation of blood flow in arteries of
cardiovascular system. The experimental fluid could be a Newtonian
or non-Newtonian. The same dimensionless parameters – the Reynolds
and Strouhal numbers – should be used for a comparison of
Newtonian and non-Newtonian fluid in models. Experimental setup
for visualization of the flow could be used as a preliminary tool for
the fast detection of main flow features. The detected regions could
be studied in detail by the experimental setup with a high-precision
measuring device. The measured flow field should be analyzed to
detect the regions prone to vascular diseases and estimate the risk of
a disease. The described experimental setups could be used to assist
a physician during the clinical decision marking process.
Sindeev S.V., Frolov S.V., Liepsch D., Balasso A.Modeling of Flow Alterations Induced by Flow-Diverter Using Multiscale Model of Hemodynamics // Scientific article. Journal "Transactions of the TSTU", vol. 23 , Tambov. TSTU publisher house , 2017. (pdf-file) Abstract: An approach to modelling hemodynamic alterations induced by flow-diverter
placement in cerebral artery is proposed. Approach is based on the concept of multiscale model of hemodynamics, which utilized three types of models which are coupled together with corresponding boundary conditions. A patient-specific cerebral aneurysm was used for simulation studies. It was modelled two cases: pre-operational and post-operational with flow-diverter stent. The results showed that flow-diverter
stent significantly alters intra-aneurysmal flow pattern. The major part of flow was diverted toward the normal direction along the parent artery. A stagnant flow in aneurysm sac was observed. Proposed approach could be used for planning of a treatment and for evaluation of risks in the post-treatment period for patients with cerebral aneurysm.